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Bray Jr. Max Wishnofsky asked in a report "What is the caloric equivalent of one pound of body weight gained or lost? Fifty years later and with thousands of citations in the scientific literature and the lay press, Hill and his colleagues repeated the oft-used statement "an energy deficit of approximately kcal is needed to lose 1 lb of body weight" in the authoritative textbook Modern Nutrition Dieta 3500 kcal Health and Disease.
But Wishnofsky's Rule as applied is inaccurate, leaving many counseled patients wondering why their prescribed weight loss is far Dieta 3500 kcal than expected even when they rigorously adhere to their dietitian's recommendations.
Only rarely is the actual report by Wishnofsky 1 appropriately referenced and the original concept is frequently mutated e. What exactly is inaccurate and even scientifically incorrect with this half-century old dictum? The decade following World War II saw profound growth in knowledge about how humans gain and lose weight with changes in energy balance.
Disturbances in energy balance that occur with famines, chronic wasting illnesses, and obesity were just coming into focus and subjected to experimental study. A small but scientifically rigorous experimental and Dieta 3500 kcal literature was available to Wishnofsky as he began his quest to find a simple rule governing weight loss or gain.
We now recognize that most of adipose tissue fat is triglyceride and Wishnofsky correctly assigned this lipid fraction a bomb-calorimetry energy density of 9. Wishnofsky then reasoned one here g of adipose tissue has an energy content of kcal.
Wishnofsky understood the critical importance of this distinction as with fasting there are disproportionally large losses of body carbohydrate glycogen and protein with associated bound water. This result was "in striking agreement with the value of kcal obtained" from computations Dieta 3500 kcal on Bozenrad's adipose tissue samples 5. Under what conditions do these assumptions hold?
When a subject in weight equilibrium reduces energy intake without changing voluntary energy expenditure e. Assuming the subject is ingesting a low calorie macronutrient-balanced diet, weight loss will proceed in two distinct phases; a rapid weight loss phase during the first few days or weeks followed by a slower weight loss phase lasting up Dieta 3500 kcal two Dieta 3500 kcal 78.
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